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Elke schakel in de bedrijfskolom betaalt btw over de toegevoegde waarde, het verschil tussen verkoopprijs (vp) en aankoopprijs (ap). Over deze waarde wordt btw berekend tegen het geldende tarief. Elke btw-plichtige onderneming moet deze btw doorstorten aan de belastingdienst. Dit bedrag is het verschil tussen btw op verkopen en btw op aankopen. Btw is een verbruiksbelasting: uiteindelijk betaalt de consument deze btw, omdat hij deze niet kan terugvorderen

 Aankopen handelsgoederen Een onderneming

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NPB Cardiovascular

Cardiovascular System:

Heart (Chordae tendineae, endocardium, myocardium (intercalated disks), epicardium)

- Contains 4 chambers

- Left side pumps O2 rich blood

- Right side pumps poor O2 blood

- Tricuspid (atrioventricular) before Bicuspid (tri before you bi)

- Pulmonary/semilunar valve: before lungs

- Aortic/semilunar valve: before aorta

Heart Nodes

- Sinoatrial node (70)

- Atrioventricular node (50) (slowest bc nodal delay)

- Bundle of his

- Purkinje fibers (30)

Action potential in cardiac cells...

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Living organisms are made up of thousands of biomolecules—molecules produced by living systems with distinct properties and functions favored through evolution. Small, simple molecules called micromolecules (or monomers), such as water, minerals, simple sugars, and nucleotides, serve as building blocks for larger macromolecules (or polymers) like proteins, lipids, carbohydrates, and nucleic acids. Biomolecules are classified into inorganic types (e.g., water, minerals, gases) and organic types

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Definition:
DNA replication is the process of producing two identical copies of DNA from one original DNA molecule. It is bidirectional and semiconservative—each daughter DNA contains one parental (old) strand and one new strand.

Steps of DNA Replication:

  1. Unwinding of DNA:Hydrogen bonds between base pairs break.

    • Two antiparallel strands separate, starting at the origin of replication.

    • Enzyme Helicase unwinds DNA, forming a replication fork.

  2. Nucleotide Activation: Deoxyribonucleotides

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🔹 Human Eye Overview

  • A spherical organ (~2.3 cm) that allows us to perceive light, color, and depth.

  • Key Parts:

    • Sclera: Outer white protective layer.

    • Cornea: Transparent front part that allows light entry.

    • Iris: Colored muscular part controlling pupil size.

    • Pupil: Opening through which light enters.

    • Lens: Flexible structure that focuses light onto the retina.

    • Retina: Light-sensitive layer converting light to electrical impulses.

      • Cones: Detect bright light and color.

      • Rods:

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3D Bioprinting

3D bioprinting is an advanced form of additive manufacturing that uses cells and biomaterials instead of plastic or metal to print organ-like structures layer by layer. It holds great promise for regenerative medicine, drug discovery, and wound healing.

How Bioprinting Works (Three Key Steps):

  1. Pre-bioprinting – Creating a digital blueprint (often from CT/MRI scans) and preparing cell-loaded bioinks.

  2. Bioprinting – Printing the structure using bioinks and multiple printheads

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Gt theyej

1. Graphs

• Graph (G): A pair (V, E) where V is a set of vertices and E is a set of edges connecting pairs of vertices.

• Types:

o Simple Graph: No loops or multiple edges.

o Multigraph: Multiple edges allowed.

o Directed Graph (Digraph): Edges have directions.

o Weighted Graph: Edges have weights.

🔹 2. Subgraphs

• Subgraph: A graph H is a subgraph of G if V(H) ⊆ V(G) and E(H) ⊆ E(G).

• Induced Subgraph: Formed by a subset of vertices and all edges between them in G.

🔹 3. Basic

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historia

Cubismo:Referir 4 das influências do cubismo?(1) Cézanne influenciou os cubistas ao interpretar figuras com formas geométricas simples.(2)As máscaras africanas inspiraram o cubismo pelo seu estilo «primitivo».(3) A Teoria da Relatividade de Einstein trouxe novos conceitos de espaço, tempo e movimento, que impactaram a arte cubista.(4) As ideias de Freud sobre o inconsciente levaram os cubistas a substituir a imagem visual por uma imagem mental.Explicitar 4 das inovações formais, técnicas

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BIOMINING

One of the smallest representatives of life forms, BACTERIA, can be seen as a mixed blessing. They cause diseases to plants and animals even to human beings such as tuberculosis and leprosy on one side and they also convert milk into curd. In last couple of decades, we have identified bacteria as miners. These diminutive diggers have become assets to the mining industry eliminating traditional offensive methods which use explosives, toxic chemicals, and high temperatures (Science, Vol

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