Bioinfomatics

I. Molecular Biology Fundamentals

Genes and Genomes

  • Every cell contains a complete set of genetic instructions—the genome—encoded in DNA and organized into genes packaged on chromosomes. A gene is a specific DNA sequence that encodes a functional product (usually a protein or an RNA). Genetic variation (mutations) underlies phenotypic differences, while environmental factors also contribute to traits ​.

DNA vs. RNA

Feature DNA (Deoxyribonucleic Acid) RNA (Ribonucleic Acid)
Sugar
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WC BIT

Handoff Strategies in Cellular Networks

Handoff strategies are essential in cellular networks to maintain call quality when a mobile device moves from one cell to another. The Mobile Switching Center (MSC) facilitates the seamless transfer of calls, ensuring minimal disruption to users.

1. Handoff Prioritization:

Handoffs are given priority over new call requests. This is crucial for maintaining ongoing conversations without interruption.

Ensuring successful and infrequent handoffs is important

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dididiid

Kcat = Vmax/ (Et)...... V0 = Vmax [S] / (ɑKM  + [S])........

KI­ - dissociation constant for the inhibitor from the enzyme

Competetive Inhibiters: Affects the slope of the line, Y intercept (1/ Vmax) does not change, Km does Change (when A is high slope gets steeper and line moves closer to origin)

UnCompetetive Inhibiters: Apparent Km changes and Vmax changes (Parellel)

Mix: A is bigger and more competitive. a is less the uncompeteive. a is equal then non competeive.

Used:1 glucose; 2 ATP;

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Software 1

Here's a neat representation and explanation of the Unified Process (UP) Model along with its phases:


Unified Process (UP) Model Diagram

Time →
+----------------+----------------+----------------+----------------+
|  Inception     | Elaboration    | Construction   | Transition     |
+----------------+----------------+----------------+----------------+
|   Requirements |  Architecture  |  Development   |  Deployment    |
|    Analysis    |   Design       |  Implementation|  Testing       |
+--
...

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Adv java

Here are detailed answers to all your questions without using tables:


1. Differentiate executeQuery() and executeUpdate() with example:

The method executeQuery() is used when you want to retrieve data from the database, typically using a SELECT statement. It returns a ResultSet object which contains the data returned by the query.

Example:

ResultSet rs = statement.executeQuery
("SELECT * FROM users"); while (rs.next()) {
System.out.println(rs.getString("username")); }

The method executeUpdate(

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Computer


1. Link State Algorithm & RIP (4 Marks)

Link State Algorithm (Used in OSPF, IS-IS):

  • Objective: Each router builds a full map of the network and uses Dijkstra’s algorithm to compute the shortest path.
  • Steps:
    1. Neighbor Discovery: Routers use Hello packets to find direct neighbors.
    2. Link Cost Calculation: Measures the cost to each neighbor (bandwidth, delay).
    3. LSA Generation: Link-State Advertisements describe the router's links and costs.
    4. Flooding LSAs: LSAs are sent to all routers in the area.
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nblyih

1. Synthesis of Vitamin D
Vitamin D3 (cholecalciferol) is synthesized in the skin when 7-dehydrocholesterol reacts with UVB radiation (sunlight).

The liver converts it to 25-hydroxyvitamin D [25(OH)D], the main circulating form.

The kidneys further convert it to the active form: 1,25-dihydroxyvitamin D [1,25(OH)₂D] (calcitriol).

2. Absorption
Vitamin D2 and D3 from food/supplements are absorbed in the small intestine, especially with dietary fat.

Requires bile salts for proper absorption.

Transported

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final exam

Question Bank Topic 1 with Solutions – Net Value Functions  Question Bank #1 – Net Value Functions: L03 – Engineering Economics & Net Value Applications  Review Questions   Recall the nanoRIMS example discussed in lecture. If the net value of buying the nanoparticles is $0 (the reference), determine the net value per week of having a grad student make the nanoparticles based on the following information:  Benefit = $896/week  Cost =   Cost of consumable supplies per week   Ingredients

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input output

1. Functions of I/O Interface and Its Need
Functions of I/O Interface:

Synchronizes the speed difference between CPU and I/O devices.

Selects and addresses the appropriate I/O device for communication.

Provides control and timing signals for data transfer.

Buffers data during transfer, managing data flow between CPU and devices.

Converts data formats (e.g., serial to parallel, digital to analog and vice versa).

Detects and reports errors during data transfer.

Handles interrupts to inform CPU when

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